Influence of Sensor Coating and Topography on Protein and Nanoparticle Interaction with Supported Lipid Bilayers

09 feb 2021

Supported lipid bilayers (SLBs) have proven to be valuable model systems for studying the interactions of proteins, peptides, and nanoparticles with biological membranes. The physicochemical properties (e.g., topography, coating) of… Läs mer

Comparing Protein Adsorption onto Alumina and Silica Nanomaterial Surfaces: Clues for Vaccine Adjuvant Development

14 jan 2021

Protein adsorption onto nanomaterial surfaces is important for various nanobiotechnology applications such as biosensors and drug delivery. Within this scope, there is growing interest to develop alumina- and silica-based nanomaterial… Läs mer

Real-time nanoplasmonic sensing of three-dimensional morphological changes in a supported lipid bilayer and antimicrobial testing applications

31 okt 2020

We report the development of a real-time localized surface plasmon resonance (LSPR) biosensing strategy to detect three-dimensional morphological changes in a supported lipid bilayer (SLB) on a plasmonic substrate. The… Läs mer

Elucidating How Different Amphipathic Stabilizers Affect BSA Protein Conformational Properties and Adsorption Behavior

11 aug 2020

Natural proteins such as bovine serum albumin (BSA) are readily extracted from biological fluids and widely used in various applications such as drug delivery and surface coatings. It is standard… Läs mer

Bulk-Processed Pd Nanocube – Poly(methyl methacrylate) Nanocomposites as Plasmonic Plastics for Hydrogen Sensing

20 jul 2020

Nanoplasmonic hydrogen sensors are predicted to play a key role in safety systems of the emerging hydrogen economy. Pd nanoparticles are the active material of choice for sensor prototype development… Läs mer

Conformational flexibility of fatty acid-free bovine serum albumin proteins enables superior antifouling coatings

17 jul 2020

Bovine serum albumin (BSA) protein is widely used to fabricate antifouling coatings for nanobiotechnology applications. Numerous BSA protein options are commercially available and obtained through different purification methods, however, there… Läs mer

Unraveling How Ethanol-Induced Conformational Changes Affect BSA Protein Adsorption onto Silica Surfaces

11 jul 2020

Protein adsorption at solid-liquid interfaces is highly relevant to a wide range of applications such as biosensors, drug delivery, and pharmaceuticals. Understanding how protein conformation in bulk solution impacts adsorption… Läs mer

Unraveling how nanoscale curvature drives formation of lysozyme protein monolayers on inorganic oxide surfaces

18 jun 2020

The development of nanostructured material interfaces is critical to various application areas spanning diverse fields such as medicine, energy, and sensing. One of the most promising areas involves nanomedicine and… Läs mer

Understanding How Natural Sequence Variation in Serum Albumin Proteins Affects Conformational Stability and Protein Adsorption

13 jun 2020

Serum albumins are evolutionary conserved proteins that are found in many animal species, and purified forms are widely used in biotechnology applications, such as components within surface passivation coatings and… Läs mer

Controlling DOPA adsorption via interacting with polyelectrolytes: layer structure and corrosion resistance

24 apr 2020

Protein adsorption upon polyelectrolyte (PE) surfaces has aroused intensive attraction, but there are still few investigations on tuning protein adsorption at solid surface by controllable layer structure and surface property… Läs mer