Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation.
October 9, 2015
A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays.
Nathan J. Wittenberg, Daniel J. Klemme, Wei Beng Ng, Jeongeun Seo, Daehan Yoo, Eric Linardy, Joshua A. Jackman, Sang-Hyun Oh, Nam-Joon Cho
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