Plasmonic Nanohole Sensor for Capturing Single Virus-Like Particles toward Virucidal Drug Evaluation.

A plasmonic nanohole sensor for virus-like particle capture and virucidal drug evaluation is reported. Using a materials-selective surface functionalization scheme, passive immobilization of virus-like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays.

Published in: Small

Date: 2015-10-09

Authors: Nathan J. Wittenberg, Daniel J. Klemme, Wei Beng Ng, Jeongeun Seo, Daehan Yoo, Eric Linardy, Joshua A. Jackman, Sang-Hyun Oh, Nam-Joon Cho