Insplorion A1 Acoulyte

Combine optical spectroscopy with QCM-D. Simultaneous real time measurements with Nanoplasmonic Spectroscopy (NPS) and Quartz Crystal Microbalance with Dissipation monitoring (QCM-D).

Key features


Insplorion Acoulyte enables the combination of label-free and real-time optical and acoustic techniques. This powerful combination gives you access to complementary information that will help in understanding complex surface and thin film processes.

Deeper knowledge of your surface and material

Obtain real-time changes in dry mass (refractive index), wet (acoustic) mass, and viscoelasticity for the same sample on the same surface and at the same time.

Simultaneous measurements

Measure simultaneously under identical experimental conditions using Insplorion’s Nanoplasmonic Spectroscopy (NPS) and Q-Sense’s Quartz Crystal Microbalance with Dissipation Monitoring (QCM-D).

Ease of use

Extremely easy to use. All that is needed to install the Acoulyte is plugging it in and place it on top of your QCM-D’s window module.

NPS and QCM-D complementarity

With NPS you can determine the dry mass of your analytes while with QCM you can estimate the wet mass, allowing for the determination of water content. Both techniques also present complementary sensing depths that enable depth profiling.

A variety of applications

The Insplorion Acoulyte is suitable for a broad scope of applications: – Molecular hydration – Molecular adsorption and desorption – Conformational changes – Depth profiling – Diffusion

A wide range of materials

The Insplorion Acoulyte is compatible with all kinds of materials: – Biomolecules – Thin films – Gases – Surfactants – Polymers

Get the product information sheet to learn more about what the Insplorion Acoulyte can do for you.

Download product sheet

Nam-Joon Cho

Professor at the School of Materials Science and Engineering and School of Chemical and Biomedical Engineering, Nanyang Technological University

“The integration of NPS sensors with acoustic sensor techniques for simultaneous measurements on the same sensing surface enables unparalleled capabilities for probing the hydration and non-hydration mass properties of biological and biomaterial systems”,

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