Insplorion’s Nanoplasmonic Sensing

A versatile and extremely surface sensitive sensing technology for realtime studies of atomic/molecular changes of less than one nanometer.

Insplorion’s NPS instruments based on LSPR can study the following changes in any thin film:

  1. Impact of light triggers/photochemistry
  2. Temperature effects and/or during temp ramping between ambient to 600 C
  3. Diffusion through thin and thick (several um) porous materials such as hydrogels or mesoporous oxides
  4. Adsorption, oxidation/reduction, phase transitions (light, temp), conformational changes, corrosion, sintering etc etc

When studying any of the above, the Insplorion has the following additional advantages:

  1. Flexibility of substrate material/chemistry
  2. Continuous flow measurements both in liquid or in gas phase
  3. Measure in/on any material/coating regardless of refractive index
  4. Simultaneous UV-VIS measurement through the sample cell

The technology exploits an optical sensing principle based on state-of-the-art nanotechnology and was first presented in the well-respected research journal Science in November 2009 in an article by our four founders (full text pdf by subscription only). NPS utilizes the Localized Surface Plasmon Resonance (LSPR) in (noble) metal nanoparticles as a local sensing probe. The unique nano-architecture of Insplorion’s NPS sensors creates a much more robust, versatile and generic sensing platform making LSPR-based sensing applicable to a large number of fields in the wide research areas of material science of thin films, sensor development and biomolecular interactions. A particular advantage of NPS is its applicability at high temperatures and under harsh chemical conditions.

The animation below illustrates the principle of Insplorion’s NPS technology and how a typical measurement is conducted with the Insplorion XNano instrument.