Nanoplasmonic Ruler for Measuring Separation Distance between Supported Lipid Bilayers and Oxide Surfaces

01 okt 2018

Unraveling the details of how supported lipid bilayers (SLBs) are coupled to oxide surfaces is experimentally challenging, and there is an outstanding need to develop highly surface-sensitive measurement strategies to… Läs mer

Temperature-Induced Denaturation of BSA Protein Molecules for Improved Surface Passivation Coatings

04 sep 2018

Bovine serum albumin (BSA) is the most widely used protein for surface passivation applications, although it has relatively weak, non-sticky interactions with hydrophilic surfaces such as silica-based materials. Herein, we… Läs mer

Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles

03 sep 2018

Society is increasingly exposed to nanoparticles as they are ubiquitous in nature and introduced as man-made air pollutants and as functional ingredients in cosmetic products as well as in nanomedicine. Läs mer

Peripheral Membrane Proteins Facilitate Nanoparticle Binding at Lipid Bilayer Interfaces

13 aug 2018

Molecular understanding of the impact of nanomaterials on cell membranes is critical for the prediction of effects that span environmental exposures to nanoenabled therapies. Experimental and computational studies employing phospholipid… Läs mer

Nanoplasmonic Sensing Architectures for Decoding Membrane Curvature-Dependent Biomacromolecular Interactions

28 maj 2018

Nanoplasmonic sensors have emerged as a promising measurement approach to track biomacromolecular interactions involving lipid membrane interfaces. By taking advantage of nanoscale fabrication capabilities, it is possible to design sensing… Läs mer

Nanoplasmonic sensing and capillary electrophoresis for fast screening of interactions between phosphatidylcholine biomembranes and surfactants

01 maj 2018

Nanoplasmonic sensing (NPS), based on localized surface plasmon resonance, with sensors composed of glass covered with golden nanodisks and overlaid with a SiO2 coating was applied in this study. Egg… Läs mer

Quantitative Comparison of Protein Adsorption and Conformational Changes on Dielectric-Coated Nanoplasmonic Sensing Arrays

22 apr 2018

Nanoplasmonic sensors are a popular, surface-sensitive measurement tool to investigate biomacromolecular interactions at solid-liquid interfaces, opening the door to a wide range of applications. In addition to high surface sensitivity,… Läs mer

Counting charges on membrane-bound peptides

03 apr 2018

Quantifying the number of charges on peptides bound to interfaces requires reliable estimates of (i) surface coverage and (ii) surface charge, both of which are notoriously difficult parameters to obtain,… Läs mer

Thermal properties and segmental dynamics of polymer melt chains adsorbed on solid surfaces

12 mar 2018

The glass transition of supported polystyrene (PS) and poly(2-vinylpyridine) (P2VP) thin films in the vicinity of the substrate interface was studied by using a nanoplasmonic sensing (NPS) method. This “nanocalorimetric”… Läs mer

Thermal cis-to-trans Isomerization of Azobenzene Side Groups in Metal-Organic Frameworks investigated by Localized Surface Plasmon Resonance Spectroscopy

05 jan 2018

The energy barrier for cis-to-trans isomerization is among the key parameters for photoswitchable molecules such as azobenzene. Recently, we introduced a well-defined model system based on thin films… Läs mer