Professor David Castner

Professor Castner uses XNano in his research at the department of chemical engineering and bioengineering at University of Washington, Seattle, USA. His research is directed at obtaining detailed information about the surface composition and structure of biomaterials and the interaction of biomolecules with those biomaterials.


Professor David Castner


University of Washington, Seattle


Chemical Engineering and Bioengineering





To address these problems, he uses a multi-technique approach that combines traditional ultra-high vacuum techniques (XPS, ToF-SIMS, etc.), biosensing techniques (XNano, QCM-D, etc.), nonlinear optical techniques (e.g., sum frequency generation (SFG) vibration spectroscopy, and computational methods (molecular dynamics, Monte Carlo, etc.).

Current research projects include the characterization of model biomaterial systems (self-assembled monolayers, peptides, ordered proteins, etc.), nanoparticles, and immobilized proteins. The objective of these research projects is to improve our understanding of the relationship between the surface properties of a biomaterial and the biological reactions occurring on that material by determining, in detail, the composition, structure, spatial distribution, and orientation of surface species.

Visit Professor Castner’s page at the University of Washington’s website here.

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